ea0029p1213 | Obesity | ICEECE2012
Felipe dos Santos Ferreira Marques M.
, Cristina Tieko Mori R.
, Mitiko Okamoto M.
, Fabres Machado U.
Objective: The aim of this study was to investigate whether SUR2A (sulfonylurea receptor type 2A, ABCC9) MEF2a (myocyte enhancer factor-2a) and HIF1a (Hypoxia-inducible factor-1) can influence glucose uptake in oxidative muscle soleus by regulating GLUT4 expression.Methods: Insulin resistance was induced in male Wistar rats by inducing obesity with monosodium glutamate (MSG). At the age 3 months, half control and MSG-treated animals started receiving 0.1...